Non-equilibrium allele frequency spectra via spectral methods

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Non-equilibrium allele frequency spectra via spectral methods.

A major challenge in the analysis of population genomics data consists of isolating signatures of natural selection from background noise caused by random drift and gene flow. Analyses of massive amounts of data from many related populations require high-performance algorithms to determine the likelihood of different demographic scenarios that could have shaped the observed neutral single nucle...

متن کامل

Non-equilibrium theory of the allele frequency spectrum.

A forward diffusion equation describing the evolution of the allele frequency spectrum is presented. The influx of mutations is accounted for by imposing a suitable boundary condition. For a Wright-Fisher diffusion with or without selection and varying population size, the boundary condition is lim(x downward arrow0)xf(x,t)=thetarho(t), where f(.,t) is the frequency spectrum of derived alleles ...

متن کامل

The non-equilibrium allele frequency spectrum in a Poisson random field framework.

In population genetic studies, the allele frequency spectrum (AFS) efficiently summarizes genome-wide polymorphism data and shapes a variety of allele frequency-based summary statistics. While existing theory typically features equilibrium conditions, emerging methodology requires an analytical understanding of the build-up of the allele frequencies over time. In this work, we use the framework...

متن کامل

Non equilibrium spectra of degenerate relic neutrinos

We calculate the exact kinetic evolution of cosmic neutrinos during the epoch previous to Big Bang Nucleosynthesis, in the case when a large neutrino asymmetry exists. By solving numerically the Boltzmann kinetic equations for the neutrino distribution functions, we find the momentum-dependent corrections to the equilibrium spectrum of neutrinos and discuss their phenomenological implications. ...

متن کامل

User Profiling via Spectral Methods

User profiling is a useful primitive for constructing personalised services, such as content recommendation. In the present paper we investigate the feasibility of user profiling in a distributed setting, with no central authority and only local information exchanges between users. We compute a profile vector for each user (i.e., a lowdimensional vector that characterises her taste) via spectra...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Theoretical Population Biology

سال: 2011

ISSN: 0040-5809

DOI: 10.1016/j.tpb.2011.02.003